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Disappearing insects, and forensics uncovered: Books in brief Nature (IF 49.962) Pub Date : 2022-04-11
Andrew Robinson reviews five of the week’s best science picks.
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Genetic origins of schizophrenia find common ground Nature (IF 49.962) Pub Date : 2022-04-11 Conrad O. Iyegbe, Paul F. O’Reilly
Rare and common genetic variants associated with schizophrenia.
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Climate change — four decades of missed opportunities Nature (IF 49.962) Pub Date : 2022-04-11
The United States should learn from its mistakes on decarbonization.
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Mapping genomic loci implicates genes and synaptic biology in schizophrenia Nature (IF 49.962) Pub Date : 2022-04-08 Vassily Trubetskoy, Antonio F. Pardi?as, Ting Qi, Georgia Panagiotaropoulou, Swapnil Awasthi, Tim B. Bigdeli, Julien Bryois, Chia-Yen Chen, Charlotte A. Dennison, Lynsey S. Hall, Max Lam, Kyoko Watanabe, Oleksandr Frei, Tian Ge, Janet C. Harwood, Frank Koopmans, Sigurdur Magnusson, Alexander L. Richards, Julia Sidorenko, Yang Wu, Jian Zeng, Jakob Grove, Minsoo Kim, Zhiqiang Li, Georgios Voloudakis
Schizophrenia has a heritability of 60–80%1, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 control individuals, we report common variant associations at 287 distinct genomic loci. Associations were concentrated in genes that are expressed in excitatory and inhibitory neurons of the
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Author Correction: T cell responses to SARS-CoV-2 spike cross-recognize Omicron. Nature (IF 49.962) Pub Date : 2022-04-08 Roanne Keeton,Marius B Tincho,Amkele Ngomti,Richard Baguma,Ntombi Benede,Akiko Suzuki,Khadija Khan,Sandile Cele,Mallory Bernstein,Farina Karim,Sharon V Madzorera,Thandeka Moyo-Gwete,Mathilda Mennen,Sango Skelem,Marguerite Adriaanse,Daniel Mutithu,Olukayode Aremu,Cari Stek,Elsa du Bruyn,Mieke A Van Der Mescht,Zelda de Beer,Talita R de Villiers,Annie Bodenstein,Gretha van den Berg,Adriano Mendes,Amy
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Jury finds University of Kansas chemical engineer guilty of hiding ties to China Nature (IF 49.962) Pub Date : 2022-04-08
After a two-week trial, Feng “Franklin” Tao was convicted on 4 of 8 charges — but a judge is reviewing the case.
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Publisher Correction: The asymmetry of antimatter in the proton. Nature (IF 49.962) Pub Date : 2022-04-08 J Dove,B Kerns,R E McClellan,S Miyasaka,D H Morton,K Nagai,S Prasad,F Sanftl,M B C Scott,A S Tadepalli,C A Aidala,J Arrington,C Ayuso,C L Barker,C N Brown,W C Chang,A Chen,D C Christian,B P Dannowitz,M Daugherity,M Diefenthaler,L El Fassi,D F Geesaman,R Gilman,Y Goto,L Guo,R Guo,T J Hague,R J Holt,D Isenhower,E R Kinney,N Kitts,A Klein,D W Kleinjan,Y Kudo,C Leung,P-J Lin,K Liu,M X Liu,W Lorenzon,N
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Why air pollution plagues a small island deep in the South Pacific Nature (IF 49.962) Pub Date : 2022-04-08
Rapa Nui has fewer than 10,000 residents but is on the receiving end of carbon monoxide from continents thousands of kilometres away.
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Rare coding variants in ten genes confer substantial risk for schizophrenia Nature (IF 49.962) Pub Date : 2022-04-08 Tarjinder Singh, Timothy Poterba, David Curtis, Huda Akil, Mariam Al Eissa, Jack D. Barchas, Nicholas Bass, Tim B. Bigdeli, Gerome Breen, Evelyn J. Bromet, Peter F. Buckley, William E. Bunney, Jonas Bybjerg-Grauholm, William F. Byerley, Sinéad B. Chapman, Wei J. Chen, Claire Churchhouse, Nicholas Craddock, Caroline M. Cusick, Lynn DeLisi, Sheila Dodge, Michael A. Escamilla, Saana Eskelinen, Ayman H
Rare coding variation has historically provided the most direct connections between gene function and disease pathogenesis. By meta-analysing the whole exomes of 24,248 schizophrenia cases and 97,322 controls, we implicate ultra-rare coding variants (URVs) in 10 genes as conferring substantial risk for schizophrenia (odds ratios of 3–50, P?
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Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity Nature (IF 49.962) Pub Date : 2022-04-08 Samuel J. Hobbs, Tanita Wein, Allen Lu, Benjamin R. Morehouse, Julia Schnabel, Azita Leavitt, Erez Yirmiya, Rotem Sorek, Philip J. Kranzusch
CBASS and Pycsar are anti-phage defense systems in diverse bacteria that use cyclic nucleotide signals to induce cell death and prevent viral propagation1,2. Phages use multiple strategies to defeat host CRISPR and restriction-modification systems3–10, but no mechanisms are known to evade CBASS and Pycsar immunity. Here we show that phages encode anti-CBASS (Acb) and anti-Pycsar (Apyc) proteins that
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High-entropy nanoparticles: Synthesis-structure-property relationships and data-driven discovery Science (IF 47.728) Pub Date : 2022-04-08 Yonggang Yao, Qi Dong, Alexandra Brozena, Jian Luo, Jianwei Miao, Miaofang Chi, Chao Wang, Ioannis G. Kevrekidis, Zhiyong Jason Ren, Jeffrey Greeley, Guofeng Wang, Abraham Anapolsky, Liangbing Hu
Science, Volume 376, Issue 6589, April 2022.
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Tuning T cell receptor sensitivity through catch bond engineering Science (IF 47.728) Pub Date : 2022-04-08 Xiang Zhao, Elizabeth M. Kolawole, Waipan Chan, Yinnian Feng, Xinbo Yang, Marvin H. Gee, Kevin M. Jude, Leah V. Sibener, Polly M. Fordyce, Ronald N. Germain, Brian D. Evavold, K. Christopher Garcia
Science, Volume 376, Issue 6589, April 2022.
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Genome-wide analysis of somatic noncoding mutation patterns in cancer Science (IF 47.728) Pub Date : 2022-04-08 Felix Dietlein, Alex B. Wang, Christian Fagre, Anran Tang, Nicolle J. M. Besselink, Edwin Cuppen, Chunliang Li, Shamil R. Sunyaev, James T. Neal, Eliezer M. Van Allen
Science, Volume 376, Issue 6589, April 2022.
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Single-cell eQTL mapping identifies cell type–specific genetic control of autoimmune disease Science (IF 47.728) Pub Date : 2022-04-08 Seyhan Yazar, Jose Alquicira-Hernandez, Kristof Wing, Anne Senabouth, M. Grace Gordon, Stacey Andersen, Qinyi Lu, Antonia Rowson, Thomas R. P. Taylor, Linda Clarke, Katia Maccora, Christine Chen, Anthony L. Cook, Chun Jimmie Ye, Kirsten A. Fairfax, Alex W. Hewitt, Joseph E. Powell
Science, Volume 376, Issue 6589, April 2022.
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Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus Science (IF 47.728) Pub Date : 2022-04-08 Richard K. Perez, M. Grace Gordon, Meena Subramaniam, Min Cheol Kim, George C. Hartoularos, Sasha Targ, Yang Sun, Anton Ogorodnikov, Raymund Bueno, Andrew Lu, Mike Thompson, Nadav Rappoport, Andrew Dahl, Cristina M. Lanata, Mehrdad Matloubian, Lenka Maliskova, Serena S. Kwek, Tony Li, Michal Slyper, Julia Waldman, Danielle Dionne, Orit Rozenblatt-Rosen, Lawrence Fong, Maria Dall’Era, Brunilda Balliu
Science, Volume 376, Issue 6589, April 2022.
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Webcast: How art and design can showcase your science Nature (IF 49.962) Pub Date : 2022-04-07
Three experts explain how to use design principles to better communicate scientific data.
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Straight-swimming bacteria and recycling CO2 — the week in infographics Nature (IF 49.962) Pub Date : 2022-04-07
Nature highlights three key graphics from the week in science and research.
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Daily briefing: A double-whammy of COVID-19 immunity Nature (IF 49.962) Pub Date : 2022-04-07
People who had COVID-19 get long-lasting benefits from vaccination. Plus, Why the WHO took two years to say COVID-19 is airborne and a growth chart for your brain.
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Girls’ maths scores drop if classmates’ parents have biased views Nature (IF 49.962) Pub Date : 2022-04-07
Data from Chinese schools show that gender-based stereotypes of maths ability pass from parents to children — and from those children to others.
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Particle’s surprise mass threatens to upend the standard model Nature (IF 49.962) Pub Date : 2022-04-07
Data from an old experiment finds that the mass of the W boson is higher than theory predicts, hinting at future breakthroughs.
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Even among ‘giant’ galaxies this one is record-setting Nature (IF 49.962) Pub Date : 2022-04-07
Newly discovered object is at least 5 megaparsecs, or 16 million light years, across — making it the biggest known structure produced by a single galaxy.
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Scorching summers can now be predicted months earlier Nature (IF 49.962) Pub Date : 2022-04-07
Sophisticated global climate model offers as much as nine months notice of extreme heat in some parts of North America.
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Ambitious trial inspires a rethink on a common ailment of pregnancy Nature (IF 49.962) Pub Date : 2022-04-07
The standard practice of treating only severe cases of high blood pressure during pregnancy might be misguided.
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In Science Journals Science (IF 47.728) Pub Date : 2022-04-07 Michael Funk, and Kip Hodges, Pamela J. Hines, Yury Suleymanov, Marc S. Lavine, Ian S. Osborne, Jelena Stajic, Beverly A. Purnell, Dan A. Erkes, Laura M. Zahn, Valda Vinson, Brent Grocholski, Yevgeniya Nusinovich, Courtney S. Malo, Leslie K. Ferrarelli, and Caroline Ash
Science, Volume 376, Issue 6589, Page 148-150, April 2022.
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Policy reforms for antibiotic use claims in livestock Science (IF 47.728) Pub Date : 2022-04-07 Lance B. Price, Laura Rogers, and Kevin Lo
Science, Volume 376, Issue 6589, Page 130-132, April 2022.
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Mutation-guided therapeutics Science (IF 47.728) Pub Date : 2022-04-07 Jacqueline Douglass
Science, Volume 376, Issue 6589, Page 147-147, April 2022.
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Targeting memories to treat trauma Science (IF 47.728) Pub Date : 2022-04-07 Philipp Mews
Science, Volume 376, Issue 6589, Page 147-147, April 2022.
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Biomaterials for boosting food security Science (IF 47.728) Pub Date : 2022-04-07 Benedetto Marelli
Science, Volume 376, Issue 6589, Page 146-147, April 2022.
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New Products Science (IF 47.728) Pub Date : 2022-04-07
Science, Volume 376, Issue 6589, Page 208-208, April 2022.
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New goals for science philanthropy Science (IF 47.728) Pub Date : 2022-04-07 France A. Córdova
Science, Volume 376, Issue 6589, Page 111-111, April 2022.
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Particle’s mass may tip the scales to new physics Science (IF 47.728) Pub Date : 2022-04-07 Adrian Cho
Science, Volume 376, Issue 6589, Page 125-125, April 2022.
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Europe tries to save Mars rover after split with Russia Science (IF 47.728) Pub Date : 2022-04-07 Daniel Clery
Science, Volume 376, Issue 6589, Page 124-124, April 2022.
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French election could buoy president’s R&D overhaul Science (IF 47.728) Pub Date : 2022-04-07 Elisabeth Pain
Science, Volume 376, Issue 6589, Page 123-123, April 2022.
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Congress restores earmarking—but with limits Science (IF 47.728) Pub Date : 2022-04-07 Jeffrey Mervis
Science, Volume 376, Issue 6589, Page 121-122, April 2022.
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New crop of mRNA vaccines aim for accessibility Science (IF 47.728) Pub Date : 2022-04-07 Jon Cohen
Science, Volume 376, Issue 6589, Page 120-121, April 2022.
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News at a glance Science (IF 47.728) Pub Date : 2022-04-07 Jeffrey Brainard
Science, Volume 376, Issue 6589, Page 116-118, April 2022.
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Taking a shot at cancer Science (IF 47.728) Pub Date : 2022-04-07 Jocelyn Kaiser
Science, Volume 376, Issue 6589, Page 126-129, April 2022.
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Spain’s Do?ana World Heritage Site in danger Science (IF 47.728) Pub Date : 2022-04-07 Juan G. Navedo, Theunis Piersma, Jordi Figuerola, and Wouter Vansteelant
Science, Volume 376, Issue 6589, Page 144-144, April 2022.
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US conservation atlas needs biodiversity data Science (IF 47.728) Pub Date : 2022-04-07 C. Carroll, R. F. Noss, and Bruce A. Stein
Science, Volume 376, Issue 6589, Page 144-145, April 2022.
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Drifting away in the Atlantic Science (IF 47.728) Pub Date : 2022-04-07 Eduardo Sampaio
Science, Volume 376, Issue 6589, Page 145-145, April 2022.
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The quest for optimal plant architecture Science (IF 47.728) Pub Date : 2022-04-07 G. Wilma van Esse
Science, Volume 376, Issue 6589, Page 133-134, April 2022.
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Population genetics meets single-cell sequencing Science (IF 47.728) Pub Date : 2022-04-07 Tomokazu S. Sumida and David A. Hafler
Science, Volume 376, Issue 6589, Page 134-135, April 2022.
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Unlocking the secrets to Janus kinase activation Science (IF 47.728) Pub Date : 2022-04-07 Ross L. Levine and Stevan R. Hubbard
Science, Volume 376, Issue 6589, Page 139-140, April 2022.
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There’s more to RNA viruses than diseases Science (IF 47.728) Pub Date : 2022-04-07 Jessica M. Labonté and Kathryn L. Campbell
Science, Volume 376, Issue 6589, Page 138-139, April 2022.
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Enhancing strength in mineralized collagen Science (IF 47.728) Pub Date : 2022-04-07 Fabio Nudelman and Roland Kr?ger
Science, Volume 376, Issue 6589, Page 137-138, April 2022.
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An upset to the standard model Science (IF 47.728) Pub Date : 2022-04-07 Claudio Campagnari and Martijn Mulders
Science, Volume 376, Issue 6589, Page 136-136, April 2022.
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In Other Journals Science (IF 47.728) Pub Date : 2022-04-07 Caroline Ash, and Jesse Smith, Pamela J. Hines, Beverly A. Purnell, Brad Wible, Caroline Ash, Stella M. Hurtley, Brent Grocholski, and Ian S. Osborne
Science, Volume 376, Issue 6589, Page 149-150, April 2022.
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In search of plan B, I found plan A Science (IF 47.728) Pub Date : 2022-04-07 Alexandria Hughes
Science, Volume 376, Issue 6589, Page 210-210, April 2022.
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Functional primordial germ cell–like cells from pluripotent stem cells in rats Science (IF 47.728) Pub Date : 2022-04-07 Mami Oikawa, Hisato Kobayashi, Makoto Sanbo, Naoaki Mizuno, Kenyu Iwatsuki, Tomoya Takashima, Keiko Yamauchi, Fumika Yoshida, Takuya Yamamoto, Takashi Shinohara, Hiromitsu Nakauchi, Kazuki Kurimoto, Masumi Hirabayashi, Toshihiro Kobayashi
Science, Volume 376, Issue 6589, Page 176-179, April 2022.
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Cryptic and abundant marine viruses at the evolutionary origins of Earth’s RNA virome Science (IF 47.728) Pub Date : 2022-04-07 Ahmed A. Zayed, James M. Wainaina, Guillermo Dominguez-Huerta, Eric Pelletier, Jiarong Guo, Mohamed Mohssen, Funing Tian, Akbar Adjie Pratama, Benjamin Bolduc, Olivier Zablocki, Dylan Cronin, Lindsey Solden, Erwan Delage, Adriana Alberti, Jean-Marc Aury, Quentin Carradec, Corinne da Silva, Karine Labadie, Julie Poulain, Hans-Joachim Ruscheweyh, Guillem Salazar, Elan Shatoff, Tara Oceans Coordinators?
Science, Volume 376, Issue 6589, Page 156-162, April 2022.
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Topological engineering of terahertz light using electrically tunable exceptional point singularities Science (IF 47.728) Pub Date : 2022-04-07 M. Said Ergoktas, Sina Soleymani, Nurbek Kakenov, Kaiyuan Wang, Thomas B. Smith, Gokhan Bakan, Sinan Balci, Alessandro Principi, Kostya S. Novoselov, Sahin K. Ozdemir, Coskun Kocabas
Science, Volume 376, Issue 6589, Page 184-188, April 2022.
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Mineralization generates megapascal contractile stresses in collagen fibrils Science (IF 47.728) Pub Date : 2022-04-07 Hang Ping, Wolfgang Wagermaier, Nils Horbelt, Ernesto Scoppola, Chenghao Li, Peter Werner, Zhengyi Fu, Peter Fratzl
Science, Volume 376, Issue 6589, Page 188-192, April 2022.
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TaCol-B5 modifies spike architecture and enhances grain yield in wheat Science (IF 47.728) Pub Date : 2022-04-07 Xiaoyu Zhang, Haiyan Jia, Tian Li, Jizhong Wu, Ragupathi Nagarajan, Lei Lei, Carol Powers, Chia-Cheng Kan, Wei Hua, Zhiyong Liu, Charles Chen, Brett F. Carver, Liuling Yan
Science, Volume 376, Issue 6589, Page 180-183, April 2022.
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Measurement of a helium tune-out frequency: an independent test of quantum electrodynamics Science (IF 47.728) Pub Date : 2022-04-07 B. M. Henson, J. A. Ross, K. F. Thomas, C. N. Kuhn, D. K. Shin, S. S. Hodgman, Yong-Hui Zhang, Li-Yan Tang, G. W. F. Drake, A. T. Bondy, A. G. Truscott, K. G. H. Baldwin
Science, Volume 376, Issue 6589, Page 199-203, April 2022.
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Orderly disorder in magic-angle twisted trilayer graphene Science (IF 47.728) Pub Date : 2022-04-07 Simon Turkel, Joshua Swann, Ziyan Zhu, Maine Christos, K. Watanabe, T. Taniguchi, Subir Sachdev, Mathias S. Scheurer, Efthimios Kaxiras, Cory R. Dean, Abhay N. Pasupathy
Science, Volume 376, Issue 6589, Page 193-199, April 2022.
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High-precision measurement of the W boson mass with the CDF II detector Science (IF 47.728) Pub Date : 2022-04-07 CDF Collaboration??, T. Aaltonen, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, G. Apollinari, J. A. Appel, T. Arisawa, A. Artikov, J. Asaadi, W. Ashmanskas, B. Auerbach, A. Aurisano, F. Azfar, W. Badgett, T. Bae, A. Barbaro-Galtieri, V. E. Barnes, B. A. Barnett, P. Barria, P. Bartos, M. Bauce, F. Bedeschi, S. Behari, G. Bellettini, J. Bellinger, D. Benjamin, A. Beretvas, A. Bhatti, K.
Science, Volume 376, Issue 6589, Page 170-176, April 2022.
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Three-dimensional visualization of nanoparticle lattices and multimaterial frameworks Science (IF 47.728) Pub Date : 2022-04-07 Aaron Michelson, Brian Minevich, Hamed Emamy, Xiaojing Huang, Yong S. Chu, Hanfei Yan, Oleg Gang
Science, Volume 376, Issue 6589, Page 203-207, April 2022.
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Investing in what matters most Science (IF 47.728) Pub Date : 2022-04-07 Steven Mana’oakamai Johnson
Science, Volume 376, Issue 6589, Page 141-141, April 2022.
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Gender, biology, and behavior Science (IF 47.728) Pub Date : 2022-04-07 Barbara J. King
Science, Volume 376, Issue 6589, Page 142-142, April 2022.
更新日期：2022-04-08
Contents have been reproduced by permission of the publishers.
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